Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss in the developed countries and is caused by both environmental and genetic factors.A recent study (Tuo et al., PNAS) reported an association between AMD and a single nucleotide polymorphism (SNP) (rs3793784) in the ERCC6 (NM_000124) gene.The risk allele also inc
Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper
Programmed cell death, or apoptosis, is a highly conserved cellular process that is crucial for tissue homeostasis under normal development as well as environmental stress.Misregulation of apoptosis is linked to many developmental defects and diseases such as tumour formation, autoimmune diseases and neurological disorders.In this paper, we show a
Parametric study on stress distribution of thin disk specimen of rupture disk corrosion test influencing SCC initiation using finite element analysis
Rupture disk corrosion test (RDCT) method has been recently developed for real-time measurement of initiation of stress corrosion cracking BAKING CUPS LARGE (SCC) in a high-temperature water.This work presents a parametric study on the stress distribution of a thin disk specimen of RDCT to consider the fixture shape and friction using finite elemen